2. What is CRS? What are it’s complications? . CRS stands for Congenital Rubella Syndrome. CRS arises when women get infected with the Rubella virus in the early stages of pregnancy. Infection of the foetus occurs when the Rubella virus spreads from placenta and enters the foetal circulation. . CRS is associated with spontaneous abortion, premature delivery and still birth . . 12-30% of women in the reproductive age group are susceptible tp rubella infection. 85% of infants are affected, when born to women infected with Rubella during the 1st trimester of pregnancy.
3. What are complications of Measles in pregnancy? . Measles infection during pregnancy can lead to increased rates of premature labour and low birth weight.
4. What are complications of Mumps in pregnancy? . Mumps that occur in Pregnant women is generally benign. Like other infections, there is a theoretical risk that mumps during the early months of pregnancy may cause complications.
5. What are the available recommendations for MMR during preconception counselling? Is MMR vaccine preferred over Rubella vaccine? . FOGSI GCPR on preconception care, 2016 recommends MMR combination vaccine. MMR is preferred over Rubella vaccine alone for the purpose of routine pre-conceptional vaccination.
6. Is serological screening mandatory before MMR vaccination? . As per FOGSI GCPR, 2016 women in pre-conceptional period should be screened for rubella infection and vaccinated if non-immune. Serological testing for Rubella however is not essential before vaccinating all women.
7. How long should pregnancy be avoided after vaccination with MMR vaccine? . Pregnancy should be avoided for one month following vaccination with MMR vaccine.
8. What if woman conceive within one month of MMR vaccination or is already pregnant? . Pregnant woman should not be vaccinated with MMR. As per CDC if a pregnant woman is inadvertently vaccinated or becomes pregnant within 4 weeks after MMR vaccination, She should be counseled about the theoretical basis of concern for the foetus: however, MMR vaccination during pregnancy should not be considered a reason to terminate pregnancy.
9. How MMR vaccine is administered? . MMR vaccine is administered subcutaneous injection preferably: although it can be given by intramuscular injection also, In the deltoid region or in the anterolateral are of the thigh.
(Please refer to prescribing information (leaflet) of vaccine for detailed information)